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Allele : Gt(ROSA)26Sor<tm1(Cacna1c*)Red> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ricardo Dolmetsch
Primary Identifier  MGI:5508369 Allele Type  Targeted
Attribute String  Conditional ready, Epitope tag, Inserted expressed sequence, No functional change Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct introduced into the locus a FLAG and Myc-tagged rat Cacna1c cDNA encoding channels with the T1036Y (dihydropyridine insensitive mutation) and the G406R (Timothy syndrome type 1 mutation, FMTYGR) mutations. A floxed stop cassette prevents expression of the inserted sequence until Cre-mediated recombination takes place.
  • mutations:
  • Insertion
  • synonyms:
  • CaV1.2<TS>,
  • CaV1.2<TS>,
  • Rosa26<FMTYGR>,
  • Rosa26<FMTYGR>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

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10 Publication categories

Trail: Allele




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