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Allele : Gt(ROSA)26Sor<tm2(Pik3ca*)Dsa> gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Dieter Saur
Primary Identifier  MGI:5510667 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct inserted into the locus an FRT site, floxed neomycin resistance cassette with 4 polyadenylation sequences, a cDNA encoding a constitutively active form of Pik3ca with an amino acid substitution of arginine for histidine at position 1047 (H1047R), a polyadenyation sequence and an FRT site. Cre-mediated recombination is required to achieve expression.
  • mutations:
  • Insertion
  • synonyms:
  • LSL-PIK3CA<H1047R>,
  • LSL-PIK3CA<H1047R>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

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Trail: Allele




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