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Allele : Klra5<tm1.2Glec> killer cell lectin-like receptor, subfamily A, member 5; targeted mutation 1.2, Georges Leclercq

Primary Identifier  MGI:5512899 Allele Type  Targeted
Attribute String  Null/knockout Gene  Klra5
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the neomycin resistance cassette and left exons 2 and 3 floxed. Cre-mediated recombination removed exons 2 and 3. FACS analysis confirmed the absence of protein expression in cells from fetal day 17 spleen and thymus and adult bone marrow and spleen.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ly49E<KO>,
  • Ly49E<KO>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele