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Allele : Tgfb1<tm3.1Flv> transforming growth factor, beta 1; targeted mutation 3.1, Richard A Flavell

Primary Identifier  MGI:5514235 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Tgfb1
Transmission  Germline Strain of Origin  (129S1/SvImJ x NOD/ShiLtJ)F1
Is Recombinase  false Is Wild Type  false
description  Recombination occurred in ES cells derived from NOD/129 F1 mice
molecularNote  An FRT flanked neo cassette followed by a loxP site was inserted into intron 2. A second loxP site was inserted in intron 1. ES cells targeted to th NOD chromosome were selected. The neo selection cassette was then removed from properly targeted ES cells by flp recombinase expression leaving exon 2 flanked by loxP sites.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele