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Allele : Kl<tm1.2Tel> klotho; targeted mutation 1.2, Tobias E Larsson
Primary Identifier  MGI:5515329 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kl
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neomycin resistance cassette and left exon 2 floxed. Cre-mediated recombination removed exon 2. Western blot analysis confirmed the absence of protein expression in the kidney.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • beta-KL<->,
  • beta-KL<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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