Primary Identifier | MGI:5515364 | Allele Type | Chemically induced (ENU) |
Attribute String | Hypomorph | Gene | Setdb1 |
Inheritance Mode | Dominant | Strain of Origin | FVB/N |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A T-to-C single point mutation in exon 21 is predicted to result in a V1248A amino acid substitution in the encoded protein. Reduced amounts of encoded protein were detected on Western blot of embryonic tissue, suggesting that this allele is hypomorphic. |