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Allele : Setdb1<MommeD17> SET domain, bifurcated 1; modifier of murine metastable epialleles, D17

Primary Identifier  MGI:5515364 Allele Type  Chemically induced (ENU)
Attribute String  Hypomorph Gene  Setdb1
Inheritance Mode  Dominant Strain of Origin  FVB/N
Is Recombinase  false Is Wild Type  false
molecularNote  A T-to-C single point mutation in exon 21 is predicted to result in a V1248A amino acid substitution in the encoded protein. Reduced amounts of encoded protein were detected on Western blot of embryonic tissue, suggesting that this allele is hypomorphic.
  • mutations:
  • Single point mutation
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele