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Allele : Npr1<tm1.1Rsha> natriuretic peptide receptor 1; targeted mutation 1.1, Rameshwar K Sharma
Primary Identifier  MGI:5516490 Allele Type  Targeted
Gene  Npr1 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 14 was replaced with a floxed neomycin resistance cassette and a modified exon 14 in which the 669WTAPELL675 motif was deleted. This domain is critical for the transduction of the atrial natriuretic peptide signal. Cre-mediated recombination removed the neomycin resistance cassette.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • 669WTAPELL675<->,
  • 669WTAPELL675<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories

Trail: Allele




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