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Allele : Tg(Pcp2-ATXN1*30Q*S776D)2Horr transgene insertion 2, Harry T Orr
Primary Identifier  MGI:5518614 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Pcp2-ATXN1*30Q*S776D)2Horr
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene consists of a mouse Pcp2 promoter driving the expression of a human ATXN1 (SCA1) cDNA with 30 CAG repeats and a serine to aspartic acid change at amino acid 776 (S776D). The Pcp2 promoter targets transgene expression to Purkinje cells. Transgene expression was confirmed by Western blot analysis of cerebellar extracts.
  • mutations:
  • Insertion
  • synonyms:
  • ATXN1[30Q]-D776,
  • ATXN1[30Q]-D776
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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