Primary Identifier | MGI:5519049 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Del(16Hspa13-App)3Yah |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
Is Recombinase | false | Is Wild Type | false |
description | Phenotypic Similarity to Human Syndrome: Monosomy 21 J:223518 |
molecularNote | Chr 16 contains a ~10.0 Mb deletion generated in ES cells by Cre-mediated recombination between loxP sites that had been introduced into Hspa13 (formerly Stch) and App by homologous recombination using targeting vectors from the Mutagenic Insertion and Chromosome Engineering Resource (MICER). |