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Allele : H2-Ab1<b-tm1.1Jssh> histocompatibility 2, class II antigen A, beta 1; targeted mutation 1.1, Jeoung-Sook Shin
Primary Identifier  MGI:5521551 Allele Type  Targeted
Attribute String  Not Specified Gene  H2-Ab1
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin resistance cassette was inserted upstream of a modified exon 4 in which nucleotide substitutions (CACAGGAGTCAGAAA to CACAGATCTCAAAGG) result in the amino acid substitution of arginine for lysine at position 253 (K253R). This mutation prevents ubiquitination. Cre-mediated recombination removed the neomycin resistance cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • H2-Ab1<tm1.1Jssh>,
  • H2-Ab1<tm1.1Jssh>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele




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