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Allele : Epas1<tm1.1Fsl> endothelial PAS domain protein 1; targeted mutation 1.1, Frank Lee
Primary Identifier  MGI:5518445 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Epas1
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 12 was replaced with one with nucleotide substitutions (GGC>TGG) that result in the amino acid substitution of glycine with tryptophan at position 536 (p.G536W). Cre-mediated recombination removed the loxP site flanked neomycin resistance gene cassette that was inserted into intron 12.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Hif2a<G536W>,
  • Hif2a<G536W>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

5 Publication categories

Trail: Allele




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