| Primary Identifier | MGI:5523909 | Allele Type | Targeted |
| Gene | Trp53 | Transmission | Germline |
| Strain of Origin | 129S2/SvPas | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Mice carrying a conditional Trp53 allele with a nonsense mutation in exon 10 were crossed to Tg(Pgk1-cre)1Lni mice to excise the floxed stop cassette. The resultant allele produces a Trp53 mRNA encoding a protein lacking the last 31 amino acids (the C terminal domain; CTD). |
