Primary Identifier | MGI:5523956 | Allele Type | Chemically induced (ENU) |
Gene | Pax3 | Inheritance Mode | Semidominant |
Strain of Origin | C57BL/6J or CBA/CaJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | ENU mutagenesis induced a nonsense mutation that results in the amino acid substitution of a stop codon for lysine at position 107 (K107X). Western blot analysis confirmed the absence of protein expression in E10.5 embryos. |