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Allele : Trp53<tm2.1Tldo> transformation related protein 53; targeted mutation 2.1, Franck Toledo

Primary Identifier  MGI:5523990 Allele Type  Targeted
Gene  Trp53 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  Mice carrying a conditional Trp53 allele lacking the AS (Alternative Splicing) exon were crossed to Tg(Pgk1-cre)1Lni mice to excise the stop cassette. The resultant allele produces mRNA from which only Trp53 proteins with the 'classical' C terminal domain can be synthesized.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele