| Primary Identifier | MGI:5523993 | Allele Type | Targeted |
| Attribute String | Inserted expressed sequence | Gene | Trp53 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector was constructed with a floxed transcriptional stop sequence, the Trp53 coding exons except for exon AS (Alternative Splicing), and a diphtheria toxin (DTA) gene. The linearized vector was electroporated into ES cells to undergo homologous recombination. Germline transmission of the mutated coding sequence was verified. |
