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Allele : Irs1<tm2Mfw> insulin receptor substrate 1; targeted mutation 2, Morris F White

Primary Identifier  MGI:7562477 Allele Type  Targeted
Gene  Irs1 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Serine codon 302 (AGC) in exon 1 was changed to alanine (GCC) (p.S302A) through homologous recombination with a mutagenized cDNA. The mutation prevents phosphorylation of the residue in the encoded peptide.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Irs1 S302A,
  • Irs1 S302A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele