|  Help  |  About  |  Contact Us

Allele : Hltf<tm1.2Geno> helicase-like transcription factor; targeted mutation 1.2, Genoway

Primary Identifier  MGI:5532313 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hltf
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 11. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 12. Flp-mediated recombination removed the neomycin resistance cassette. Cre-mediated recombination removed exons 11 and 12. Western blot analysis confirmed the absence of protein expression in the heart, lung, liver, kidney and spleen.
  • mutations:
  • Intragenic deletion,
  • Insertion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele