| Primary Identifier | MGI:5532313 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hltf |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 11. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 12. Flp-mediated recombination removed the neomycin resistance cassette. Cre-mediated recombination removed exons 11 and 12. Western blot analysis confirmed the absence of protein expression in the heart, lung, liver, kidney and spleen. |