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Allele : Elovl1<tm1.1Akih> ELOVL fatty acid elongase 1; targeted mutation 1.1, Akio Kihara
Primary Identifier  MGI:5532707 Allele Type  Targeted
Attribute String  Null/knockout Gene  Elovl1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 8. Cre-mediated recombination removed exons 2 through 8 and left the FRT-flanked neomycin resistance cassette intact. Fatty acid elongation activity towards C22-CoA is greatly reduced in the skin, brain and liver.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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