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Allele : Bub1b<tm1.1Hsl> BUB1B, mitotic checkpoint serine/threonine kinase; targeted mutation 1.1, Hyunsook Lee
Primary Identifier  MGI:5543300 Allele Type  Targeted
Gene  Bub1b Transmission  Germline
Strain of Origin  129 Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 6 is replaced with an FRT-flanked neomycin resistance cassette with a 5' loxP site and a modified exon 6 in which nucleotide substitutions (AAA to AGG) result in the amino acid substitution of arginine for lysine at position 243 (K243R). Flp-mediated recombination removed the neomycin resistance cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • BubR1<K243R>,
  • BubR1<K243R>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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