| Primary Identifier | MGI:5544573 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Svop |
| Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NCrl)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 3. Cre-mediated recombination removed the neomycin resistance cassette, exon 2 and exon 3. Western blot analysis confirmed the absence of protein expression in the brain. |