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Allele : Tg(SNCA*A30P)192Rwm transgene insertion 192, Richard Wade-Martins

Primary Identifier  MGI:5543905 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(SNCA*A30P)192Rwm
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of a 135 kb BAC clone, PAC-27 M07, containing the complete 111 kb human SNCA genomic DNA locus with the Parkinson Disease-associated A30P mutation, flanked by 18 kb of 5' and 6 kb of 3' genomic DNA sequence which includes the promoter. Western blot analysis confirmed expression of the human protein in the brain. Line 192 contains a single copy insertion in chromosome 15.
  • mutations:
  • Insertion
  • synonyms:
  • SNCA-A30P,
  • SNCA-A30P
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele