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Allele : Tgfbr1<tm1.1Hcd> transforming growth factor, beta receptor I; targeted mutation 1.1, Harry C Dietz
Primary Identifier  MGI:5543795 Allele Type  Targeted
Gene  Tgfbr1 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  Site-directed mutagenesis was performed to substitute methionine 318 with arginine (ATG->CGG; adenine to cytosine, and thymine to guanine at nucleotides 952 and 953 respectively) in exon 5 of the targeted gene. A loxP-flanked neomycin selection cassette was placed in intron 6. Cre-mediated recombination removed the floxed neo cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Tgfbr1<M318R>,
  • Tgfbr1<M318R>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele




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