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Allele : Tg(MS4A1-cre/ERT2)1Mjsk transgene insertion 1, Mark J Shlomchik
Primary Identifier  MGI:5545930 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(MS4A1-cre/ERT2)1Mjsk
Strain of Origin  Not Specified Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  A BAC (RP11-729B4) containing the human MS4A1 (hCD20) locus was modified by insertion of an IRES-cre/ERT2 (cre recombinase-mutated human estrogen receptor ligand-binding domain fusion) cassette into the 3' untranslated region of the gene. The modified BAC vector was used to generate a transgene that expresses a tamoxifen-inducible cre specifically in B cells. MS4A1 is also expressed from this allele. Line numbers are not available.
  • mutations:
  • Insertion
  • synonyms:
  • hCD20Tam<Cre>,
  • hCD20-TamCre,
  • hCD20Tam<Cre>,
  • hCD20-TamCre
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

Trail: Allele

21 Publication categories

Trail: Allele




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