| Primary Identifier | MGI:5547984 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Nacc1 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of the coding sequence for the BTB/POZ domain (exon 2). A floxed neomycin resistance cassette was inserted downstream of exon 3. Cre-mediated recombination removed the neomycin resistance cassette, exon 2 and exon 3. Western blot analysis confirmed the absence of protein expression in chondrocytes. |
