Primary Identifier | MGI:5548125 | Allele Type | Targeted |
Attribute String | Inducible, Recombinase | Gene | Sohlh1 |
Transmission | Germline | Strain of Origin | (C57BL/6NTac x 129S6/SvEvTac)F1 |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A targeting vector was constructed to insert a cre/ERT2-Frt-neo-Frt cassette into the Sohlh1 gene by homologous recombination. The cre cassette was inserted at the ATG start codon, replacing exons 1-8. Chimeras were bred to C57BL/6 mice, and F1 animals were crossed to flp-expressing mice to remove the neo marker. |