| Primary Identifier | MGI:5550551 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Il6ra |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 2, and an additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 2 and 3. Western blot analysis confirmed the absence of protein expression in the liver, spleen, thymus and lymph node. |
