Primary Identifier | MGI:5550566 | Allele Type | Targeted |
Gene | Comp | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The allele was generated by site directed mutagenesis that delete 3 bp in exon 13 (TGACGATGAT---AATG). This mutation (D469del) occurs in the TSP3 region of the protein. Cre-mediated recombination removed the floxed selection cassette in intron 16. Western blot analysis confirmed expression of the monomeric protein. |