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Allele : Igh-J<tm2.1(4E10)Lave> immunoglobulin heavy chain, joining region; targeted mutation 2.1, Laurent Verkoczy
Primary Identifier  MGI:5550246 Allele Type  Targeted
Gene  Igh-J Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The J1-4 regions were replaced with a J558 H10 family promoter, the H10 split leader sequence, a rearranged human heavy chain sequence of the HIV-1 antibody 4E10 (a self-/polyreactive, anti-gp41 BnAb) and a floxed neomycin resistance (neo) cassette. Cre-mediated recombination removed the neo cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • 4E10 VH<+>,
  • 4E10 VH<+>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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