| Primary Identifier | MGI:5550457 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Card14 |
| Transmission | Chimeric | Strain of Origin | C57BL/6N-A<tm1Brd> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Glycine codon 117 was changed to a serine codon (p.G117S) through a G-to-A point mutation, and an FRT flanked neomycin selection cassette inserted into intron 5. Subsequent breeding to an FLP1 expressing transgenic excised the neomycin selection cassette. The mutation mimics a psoriasis-associated mutation in human. |
