| Primary Identifier | MGI:5550459 | Allele Type | Targeted |
| Gene | Card14 | Transmission | Chimeric |
| Strain of Origin | C57BL/6N-A<tm1Brd> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Glutamic acid codon 138 was changed to an alanine codon (p.E138A) through an A-to-C point mutation, and an FRT flanked neomycin selection cassette inserted into intron 5. Subsequent breeding to an FLP1 expressing transgenic excised the neomycin selection cassette. The mutation mimics a psoriasis-associated mutation in human. |
