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Allele : Col1a1<tm1(tetO-Fos)Wag> collagen, type I, alpha 1; targeted mutation 1, Erwin F Wagner
Primary Identifier  MGI:5555845 Allele Type  Targeted
Attribute String  Inducible, Inserted expressed sequence, RMCE-ready Gene  Col1a1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
description  The allele was made in KH2 cells that carry Gt(ROSA)26Sortm1(rtTA*M2)Jae and Col1a1tm13(neo/hygro*)Jae. This allele was generated with Col1a1tm13(neo/hygro*)Jae.
molecularNote  KH2 ES cells containing Gt(ROSA)26Sortm1(rtTA*M2)Jae and Col1a1tm13(neo/hygro*)Jae were retargeted with a "flp-in plasmid" containing a tetracycline responsive element (TRE or tetO) and FLAG-tagged Fos cDNA sequence. A flpe-recombinase plasmid to facilitated integration into the 3' UTR region.
  • mutations:
  • Insertion
  • synonyms:
  • Col<TetO-Fos>,
  • Col<TetO-Fos>,
  • Col1a1<TetOP-c-Fos>,
  • Col1a1<TetOP-c-Fos>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

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7 Publication categories

Trail: Allele




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