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Allele : Rock1<tm1.2Itl> Rho-associated coiled-coil containing protein kinase 1; targeted mutation 1.2, inGenious Targeting Laboratory
Primary Identifier  MGI:5556290 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rock1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT- and loxP-flanked neomycin resistance cassette was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the neomycin resistance cassette. Cre-mediated recombination removed exon 5. Western blot analysis confirmed the absence of protein expression in the heart.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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