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Allele : Slx4<tm1.2Jrou> SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae); targeted mutation 1.2, John Rouse
Primary Identifier  MGI:5559219 Allele Type  Targeted
Attribute String  Null/knockout Gene  Slx4
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 8. An FRT-flanked neomycin resistance cassette, IRES and splice donor with a 5' loxP site was inserted downstream of exon 9. Flp-mediated recombination removed the selection cassette and left exons 8 and 9 floxed. Western blot analysis confirmed the absence of protein expression in mosue embryonic extracts.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele




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