| Primary Identifier | MGI:5558867 | Allele Type | Targeted |
| Gene | Fbn1 | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 38 was replaced with a floxed neomycin resistance cassette and a modified exon 38 in which nucleotide substitutions result in the amino acid substitution of glutamic acid for aspartic acid at position 1545 (D1545E). This mutation destroys the integrin binding site. Cre-mediated recombination removed the selection cassette. |
