| Primary Identifier | MGI:5558868 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Fbn1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 38 was replaced with a floxed neomycin resistance cassette and a modified exon 38 in which nucleotide substitutions result in the amino acid substitution of cysteine for tryptophan at position 1572 (W1572C). This mutation is associated with stiff skin syndrome (SSS) in human patients. Cre-mediated recombination removed the selection cassette. |
