| Primary Identifier | MGI:5560296 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence, Reporter | Gene | Tg(Tmc1/mCherry)2Ajg |
| Strain of Origin | (C57BL/6 x SJL)F2 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene was created by targeted insertion of mCherry protein coding sequence into the bacterial artificial chromosome (BAC) MSMG01-526L10. The mCherry sequence was integrated at the stop codon of Tmc1, the only gene in the BAC. The integration site was not investigated. This C-terminal fusion is expressed in the sensory hair cells of the inner ear. Confocal fluorescence images of inner hair cells from transgenic mice at postnatal day 8 (P8) show the transgenic protein localizes predominantly to the tips of the shorter rows of stereocilia. Line 2 carries 7 copies of the transgene. |
