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Allele : Stx1a<tm1Migar> syntaxin 1A (brain); targeted mutation 1, Michihiro Igarashi

Primary Identifier  MGI:5563140 Allele Type  Targeted
Gene  Stx1a Transmission  Germline
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 6 was replaced with one in which an A to G mutation results in the amino acid substitution of arginine with glycine at position 151 (p.R151G). This missense mutation interfers with the interaction between the peptide encoded by this allele and the Camk2 peptide. An FRT site flanked neomycin resistance gene cassette was inserted into intron 7.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • syntaxin-1A (R151G),
  • syntaxin-1A (R151G)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele