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Allele : Tg(Pcp2-COP4*H134R/EYFP)U126Isop transgene insertion U126, Philippe Isope

Primary Identifier  MGI:5568417 Allele Type  Transgenic
Attribute String  Reporter Gene  Tg(Pcp2-COP4*H134R/EYFP)U126Isop
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  I.M.A.G.E. clone BAC RP24-186D18 was modified to express a cDNA encoding humanized COP4 (also called channelrhodopsin-2 or ChR2) carrying an H134R (histidine 134 arginine) mutation fused to EYFP (ChR2(H134R)EFYP) under the control of the mouse Pcp2 gene regulatory elements. High expression is found in Purkinje cells of the cerebellum as well as rod bipolar cells of the retina.
  • mutations:
  • Insertion
  • synonyms:
  • L7-ChR2(H134R)-eYFP,
  • L7-ChR2,
  • L7-ChR2,
  • L7-ChR2(H134R)-eYFP
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele