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Allele : Bmpr2<tm1.1Pley> bone morphogenetic protein receptor type 2; targeted mutation 1.1, Patricio A Leyton

Primary Identifier  MGI:5568728 Allele Type  Targeted
Attribute String  Reporter Gene  Bmpr2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  An EGFP gene with a stop codon was fused to exon 11. Exon 12 was replaced with a floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. Western blot analysis confirmed the expression of a smaller than normal protein (~100 kDa). However, cell membrane localization of the truncated protein is normal.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Bmpr2<deltatd>,
  • Bmpr2<deltatd>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele