| Primary Identifier | MGI:5566794 | Allele Type | Targeted |
| Gene | Jak2 | Transmission | Germline |
| Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 21 was replaced with one in which nucleotide substitutions result in the amino acid substitutions of phenyalanine for tyrosine at positions 1007 and 1008 in the activation loop. Cre-mediated recombination removed a floxed neomycin resistance cassette inserted upstream of exon 20. Western blot analysis confirmed normal protein levels. |
