| Primary Identifier | MGI:5567993 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Npr2 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 1 of Npr2 was replaced with an nls-lacZ (nuclear localization sequence-lacZ) expression cassette and polyadenylation sequence by homologous recombination in ES cells. The targeting vector also contained a self-excising cre recombinase-neo cassette (cre is expressed from a testis-specific promoter, so the neo is deleted in the male germline). No Npr2 protein was detected in samples from homozygotes. |
