| Primary Identifier | MGI:5569908 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Mylk3 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A floxed neomycin resistance cassette was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 5. Cre-mediated recombination removed the selection cassette and exon 5. This deletion results in the elimination of the first coding exon of the catalytic domain and a frameshift of the subsequent downstream exons. Northern blot analysis confirmed the absence of transcript expression. |
