Primary Identifier | MGI:5572019 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Bmp2 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 3 and an frt flanked neomycin resistance cassette, second loxP site, and a human alkaline phosphatase gene were inserted downstream of exon 3. The neo cassette was removed by flp-mediated recombination. Cre-mediated recombination removed exon 3. |