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Allele : Traf3<m1Btlr> TNF receptor-associated factor 3; mutation 1, Bruce Beutler

Primary Identifier  MGI:5578024 Allele Type  Chemically induced (ENU)
Gene  Traf3 Inheritance Mode  Recessive
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false Project Collection  Beutler Mutagenetix
molecularNote  ENU mutagenesis induced a T to A transversion at base pair 111,261,576 (v38) on Chromosome 12, or base pair 95,207 in the GenBank genomic region NC_000078. The mutation corresponds to residue 1,395 in the mRNA sequence NM_001286122 within exon 12 of 12 total exons (isoform 1) and residue 1,581 in the mRNA sequence NM_011632 within exon 10 of 10 total exons (isoform 2). The mutation results in an valine (V) to aspartic acid (D) substitution at position 407 (V407D) in the ENSMUSP00000021706 isoform and a V to D substitution at position 382 (V382D) in the ENSMUSP00000112517 isoform.
  • mutations:
  • Single point mutation
  • synonyms:
  • hulk,
  • hulk
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele