Primary Identifier | MGI:5578562 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(HSV-Hoxd4)70Cka |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transresponder transgene contains mouse Hoxd4 cDNA under the control of the VP-16 responsive HSV immediate early (IE) promoter. A c-myc (Myc) epitope tag and SV40 poly-A sequence is inserted at the 3' end of the coding region. Transgene expression is activated when a transresponder mouse is combined with a transactivator mouse carrying the viral coactivator VP16 under the control of a promoter of interest. Expression is limited to regions in the mouse embryo where VP16 is present. |