Primary Identifier | MGI:5578567 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence, Reporter | Gene | Tg(Isl1-lacZ)5Cka |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgenic construct contains the lacZ reporter under the control of a 10 kb Isl1 fragment. The Isl1 insert consists of a region beginning 8.5 kb downstream of the transcription start site and ending 7 kb downstream of the transcription stop site, and including an enhancer regulatory element. LacZ reporter activity parallels endogenous gene expression in the developing heart as well as visceral and posterior mesoderm. |