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Allele : Lrrc8a<tm1.1Geha> leucine rich repeat containing 8A VRAC subunit A; targeted mutation 1.1, Raif S Geha

Primary Identifier  MGI:5581436 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lrrc8a
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 and part of the following intron were replaced with a floxed neomycin selection cassette which was subsequently removed by cre excision. Immunoblotting of thymocyte lysates and FACS analysis of splenic T and B cells confirmed the absence of protein expression in homozygous mutant mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Lrrc8a<->,
  • Lrrc8a<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele