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Allele : Tg(H2-K-IL6)2Srj transgene insertion 2, Stefan Rose-John

Primary Identifier  MGI:5582513 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(H2-K-IL6)2Srj
Strain of Origin  (C57BL/6 x DBA/2)F2 Is Recombinase  false
Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Multicentric Castleman Disease, Plasma-cell type J:185153
molecularNote  The MHC class I promoter H2K drives the expression of the HHV-8 viral IL6 with a C-terminal MYC tag predominantly in hematopoietic organs and lymphocytes. Two lines were established, 1 and 2.
  • mutations:
  • Insertion
  • synonyms:
  • vIL-6tg2,
  • vIL-6tg2
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele