Primary Identifier | MGI:5585588 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Hprt1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The cDNA of the most frequent mutation of NPM1, mutA, under the control of the pCAG promoter was inserted into the Hprt locus. A stop cassette flanked by loxP sites between the promoter and the cDNA was added, allowing for the conditional expression of the mutant gene upon cre-mediated recombination. |