Primary Identifier | MGI:5588817 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tshz1 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP flanked exon2 of Tshz1 gene was removed. This allele was generated by crossing Tshz1tm2.1Garr mice with mice carrying the cre-deleter allele Tg(CMV-cre)1Cgn to remove the exon2. The in situ hybridization and immunostaining on homozygous embryos confirmed absence of transcripts and functional protein products. This is a null allele. |